Full Metal Alchemist: Brotherhood?

Brotherhood is a complete do-over of the FMA television series. The big difference is that while the original TV series didn't follow the manga very closely, Brotherhood is *very* faithful to Hiromu Arakawa's original story. Some things early on will be things you've seen before, but there are loads of new characters that didn't appear in the original TV series, and some of the basic aspects of the series (what is a homunculus?) are different.